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    STUDIA CHEMIA - Ediţia nr.1 din 2023  
         
  Articol:   PROTECTIVE EFFECTS OF ALUMINOSILICATES ON LEAD-ACETATE TOXICITY IN BROILER CHICKENS.

Autori:  DEJAN PRVULOVIĆ, DANIJELA KOJIĆ. 		 
       
         
  Rezumat:  
DOI: 10.24193/subbchem.2023.1.15

Published Online: 2023-03-27
Published Print: 2023-04-30
pp. 211-223

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The study examined the effect of dietary supplements of lead acetate (PbA) and/or aluminosilicates (zeolite and montmorillonite) on growth traits, relative organ weights, activity of liver enzymes and activity of enzymes of antioxidant protection and lipid peroxidation in liver, erythrocytes, pancreas and spleen of chickens. Weight gain, feed conversion ratio, relative weights of liver, pancreas and spleen and activity of antioxidative enzymes in pancreas and spleen were not influenced with dietary treatment. Dietary intake of PbA induces oxidative stress and promotes lipid peroxidation in liver and erythrocytes. Activities of liver enzymes (alkaline phosphatase, γ-glutamyltransferase and α-amylase) were influenced by PbA also. Aluminosilicates alone did not provoke any adverse effect and did not disturb normal biochemical and physiological homeostasis in broilers. The combined data showed that chickens fed aluminosilicates received significant protection against the effects of the PbA for most parameters measured.

Keywords: aluminosilicates; antioxidative enzymes; bentonite; chickens; erythrocytes; lead acetate; liver; montmorillonite 		 
         
     
         
         
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