AMBIENTUM BIOETHICA BIOLOGIA CHEMIA DIGITALIA DRAMATICA EDUCATIO ARTIS GYMNAST. ENGINEERING EPHEMERIDES EUROPAEA GEOGRAPHIA GEOLOGIA HISTORIA HISTORIA ARTIUM INFORMATICA IURISPRUDENTIA MATHEMATICA MUSICA NEGOTIA OECONOMICA PHILOLOGIA PHILOSOPHIA PHYSICA POLITICA PSYCHOLOGIA-PAEDAGOGIA SOCIOLOGIA THEOLOGIA CATHOLICA THEOLOGIA CATHOLICA LATIN THEOLOGIA GR.-CATH. VARAD THEOLOGIA ORTHODOXA THEOLOGIA REF. TRANSYLVAN
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Authors: AURORA MOCANU, DIANA ALEXANDRA FLOREA, GHEORGHE TOMOAIA, LUCIAN CRISTIAN POP, ANCUTA DANISTEAN, SORIN RAPUNTEAN, OSSI HOROVITZ, MARIA TOMOAIA-COTISEL.
DOI: 10.24193/subbchem.2023.3.01
Published Online: 2023-09-30
Published Print: 2023-09-30
pp. 7-18
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A nanocomposite made from hydroxyapatite (HAP) and silver nanoparticles (AgNPs), namely HAP-4.5 wt% AgNPs, is reported. HAP was prepared using a wet precipitation technique, and AgNPs were made by reducing silver nitrate with glucose in basic medium. HAP, AgNPs and HAP-4.5 wt% AgNPs composite were characterized by X-ray diffraction (XRD), SEM - energy dispersive X-ray spectroscopy (EDS) and different imagistic methods: TEM and AFM. The antibacterial effect of the HAP-4.5 wt% AgNPs nanocomposite was tested using diffusion technique in nutritive agar on two pathogenic species, one Gram-negative (Salmonella typhimurium) and one Gram-positive (Bacillus cereus) and promising results were obtained. This hydroxyapatite-silver nanocomposite can be employed as a potential antimicrobial coating for dental and orthopedic implants, or they can be utilized such as bone cements in clinical procedures.
Keywords: hydroxyapatite, silver nanoparticles, nanocomposite, antibacterial activity, pathogens
