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    STUDIA BIOLOGIA - Issue no. 1 / 2023  
         
  Article:   EXPLORING PROTEIN - PROTEIN INTERACTION IN CELL PHYSIOLOGY BY REVIEWING THE ROLE OF DYNEIN-DYNACTIN INTERACTION AS A REPRESENTATIVE EXAMPLE.

Authors:  NEELABH DATTA.
 
       
         
  Abstract:  
DOI: 10.24193/subbbiol.2023.1.06

Article history: Received: 27 February 2023; Revised: 23 March 2023; Accepted: 24 May 2023; Available online: 30 June 2023.
©2023 Studia UBB Biologia. Published by Babeş-Bolyai University.
pp. 103-118

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Protein-protein interactions are essential for the normal function of cells and are involved in various cellular processes. These interactions can occur through a variety of mechanisms, including hydrogen bonding, ionic interactions, and hydrophobic interactions. Changes in protein-protein interactions can alter the normal function of the cell and lead to various diseases. Understanding protein-protein interactions is important for the development of therapeutic approaches targeting these interactions for the treatment of diseases. In this article, I will discuss the role of protein-protein interactions in normal cellular function, the consequences of changes in these interactions, and the importance and significance of understanding these interactions by using the example of dynein-dynactin.

Keywords: protein-protein interactions, dynein, dynactin, dysregulation, cargo transport
 
         
     
         
         
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