The STUDIA UNIVERSITATIS BABE┼×-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA BIOLOGIA - Issue no. 1 / 2019  
         
  Article:   THE STORY OF ECTOINE.

Authors:  ERWIN A. GALINSKI.
 
       
         
  Abstract:  The novel amino acid derivative ectoine was discovered in 1985 as a minor compatible solute in the bacterial genus Ectothiorhodospira (Galinski et al., 1985). It has since been detected in an ever-growing number of bacterial species (to date more than 400) and a few archaeal genera (Widderich et al., 2016), but also in some eukaryotic protists (Harding et al., 2016). Due to its apparently unique stabilizing and protecting properties, ectoine has found numerous applications as a medical product in the skin and health care sector and is at present produced industrially with the halophilic Halomonas elongate at several tons per year (Kunte et al., 2014). This presentation recalls the story of ectoine from an exotic find to a sought-after natural product and the people involved in its success. We will see what molecular features make this molecule special in its interaction with proteins, DNA and membranes and address potential medical applications. In this context I will also include the latest discoveries, which will provide new insights into ectoine┬┤s novel molecular functions.

Keywords: compatible solute, ectoine, medical device, molecular interaction
 
         
     
         
         
      Back to previous page