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The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary
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Abstract: Aims: We investigated the effect of acute moderate hypoxia exposure and the effect of acute ozone exposure on exercise in norrmobaric normoxia. Material and methods: The research was performed in 4 groups of white male Wistar rats (n = 10 animals /group) with a weight of 280-300 g: Group I – control, normoxic exercise; Group II - exposed to acute O3 and normoxic exercise; Group III – exposed to acute moderate hypoxia (corresponding to a 2500 m altitude) and normoxic exercise; Group IV –combination of O3 and moderate hypoxia and normoxic exercise. The exposure to moderate hypoxia was for 3 days, 20 hours/day at values of 2500 m using hypoxic rooms. The rats were exposed to ozone for 3 days, 5 min/day. The groups were trained in normoxia daily. The exercise capacity was measured during the swim test on days 1, 2, 3 (T1, T2 and T3). Rezults: In all groups, significant increases in maximal exercise capacity occur during the course of the 3 days, compared to initial values (T1). In group II, exposed to O3 before exercise, decreases in maximal exercise capacity are found, which are significant in T3 compared to groups I, III and IV. In group III, exposed to hypoxic stress before exercise, significant increases in maximal exercise capacity are found at all moments, compared to groups I and II. In group IV, exposed to combined stress before exercise: O3, hypobaric hypoxia – significant increases in maximal exercise capacity are found at all moments, compared to groups I, II and III. Conclusions: Acute moderate hypoxia limits maximal exercise capacity in rats under normobaric normoxia conditions. Acute O3 exposure determines a significant increase in maximal exercise capacity in rats under normobaric normoxia conditions. The association of acute O3 exposure and acute moderate hypoxia exposure determines a significant increase in maximal exercise capacity in rats. The use of acute O3 exposure is recommended for increasing exercise capacity under normobaric normoxia conditions.
Keywords: acute exposure, hypobaric hypoxia, ozone, effort. |
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