The STUDIA UNIVERSITATIS BABEŞ-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

  
       
         
    STUDIA CHEMIA - Issue no. 3 / 2011  
         
  Article:   NEW 1-AZABICYCLO[3.2.2]NONANE DERIVATIVES OBTAINED BY NUCLEOPHILIC DISPLACEMENT AT CARBON C9 OF CINCHONA ALKALOIDS .

Authors:  LUMINIŢA SILAGHI-DUMITRESCU. 		 
       
         
  Abstract:  Nucleophilic substitution of mesylates prepared from cinchona alkaloids, generated new 1-azabicyclo[3.2.2]nonan derivatives by cage extension rearrangement reactions which accompanied the displacement of the leaving group. Moderate yields of substituted [3.2.2]azabicyclo derivatives were obtained when water, potassium cyanide or phthalimide nucleophiles were employed. The new substituted [3.2.2]azabicyclo derivatives were further functionalized by oxidation, reduction or condensation reactions.

Keywprds: cinchona alkaloids, SN-displacement, 1-azabicyclo[3.2.2]nonane 		 
         
     
         
         
      Back to previous page