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    STUDIA CHEMIA - Issue no. 2 / 2004  
         
  Article:   REACTIONS OF THE 3-CYANO-10-METHYL-PYRIDO[3,2-G]QUINOLIN-4-ONE.

Authors:  CLAUDIA MOLDOVAN, CASTELIA CRISTEA, IOAN ALEXANDRU SILBERG, ABDALLAH MAHAMOUD, CĂLIN DELEANU, JACQUES BARBE.
 
       
         
  Abstract:  The reaction of 3-cyano-10-methyl-pyrido[3,2-g]quinoline-4-one 1 with alkylhalides in alkaline conditions under PTC conditions is described. A mixture of N-alkyl- and O-alkyl-3-cyano-10-methyl-pyrido[3,2-g]quinoline was obtained in low yields as a consequence of an ambident nucleophile generated by 1, while the main competitive reaction appears to be the hydration of the carbonyl bond in alkaline medium.  
         
     
         
         
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