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    STUDIA BIOLOGIA - Issue no. 2 / 2003  
         
  Article:   REACŢII ALE ORGANISMULUI LA VENINUL DE ALBINE ŞI TOXICITATEA ACESTUIA.

Authors:  ADRIAN FLOREA, CONSTANTIN CRĂCIUN.
 
       
         
  Abstract:  Reactions of the Organism to the Honey Bee Venom and Its Toxicity. Despite the fact that it has been used from ancient times in the folk medicine and, in the last few decades, many important applications in the modern medicine were reported, the venom still remains, over millions of years, an efficient, basic and very potent defensive weapon of bees. In different organisms which come in contact ľ in different circumstances ľ with the bee venom, a series of modifications can occur. The magnitude of these modifications depends, of course, on the dose and the frequency of stings (or on the therapeutical/experimental administration). However, the reactions may range from the local, painful and irritating reactions, to systemic, severe toxic reactions. In special cases, when the immune system does not respond properly in the presence of the venom, the allergy or even the anaphylactic shock may evolve. Because of its importance, both as a medicine and basic research tool, the bee venom became recently a subject for extensive studies which include, among other topics, the determination of toxicity levels of the venom and also of each of its major constituents.  
         
     
         
         
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