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Tumor angiogenesis has a crucial role in tumor development and the metastasis. Initiation and angiogenesis development is a result of the interaction of two tumor-associated processes: inflammation and oxidative stress. Therefore, a better understanding of molecular mechanisms that play a key role in tumor angiogenesis-associated inflammation and oxidative stress can offer promising strategies for future anticancer therapies.

Keywords: cancer, angiogenesis, oxidative stress, inflammation