The STUDIA UNIVERSITATIS BABE┼×-BOLYAI issue article summary

The summary of the selected article appears at the bottom of the page. In order to get back to the contents of the issue this article belongs to you have to access the link from the title. In order to see all the articles of the archive which have as author/co-author one of the authors mentioned below, you have to access the link from the author's name.

 
       
         
    STUDIA BIOLOGIA - Issue no. 1 / 2007  
         
  Article:   ULTRASTRUCTURAL STUDIES CONCERNING THE REACTIVITY OF THE HIPOTHALAMIC-PITUITARY AXIX FOLLOWING L-MONOSODIUM GLUTAMATE ADMINISTRATION IN JUVENILE RABBITS.

Authors:  CONSTANTIN PUICĂ, CONSTANTIN CRĂCIUN, MIRCEA RUSU, IOANA ROMAN, MIHAI CRISTESCU.
 
       
         
  Abstract:  . Subchronic oral administration for 30 days of L-monosodic-glutamate (GLU) in a daily dose of 0.15 mg/g, body weight in immature prepubertal male rabbits, induced reactive manifestations of mediobasal hypothalamus morphology, characterized by ultrastructural alteration of the majority of neuronal cellular components: nucleus, nucleolus, mitochondria and endoplasmic reticulum. The excitotoxic effect of GLU is expressed also by the blocking in some hypothalamus regions of the axonal and dendrites myelinates processes. At the adenohypophysis level, glutamate has determined drastically reduces of the number of the electron-dense secretory granules in some cellular components associated with mitochondrial balloonization, dilatation of both smooth endoplasmic reticulum and Golgi apparatus, as well as significantly rarefaction of ribosome from cytoplasmatic structure.  
         
     
         
         
      Back to previous page