AMBIENTUM BIOETHICA BIOLOGIA CHEMIA DIGITALIA DRAMATICA EDUCATIO ARTIS GYMNAST. ENGINEERING EPHEMERIDES EUROPAEA GEOGRAPHIA GEOLOGIA HISTORIA HISTORIA ARTIUM INFORMATICA IURISPRUDENTIA MATHEMATICA MUSICA NEGOTIA OECONOMICA PHILOLOGIA PHILOSOPHIA PHYSICA POLITICA PSYCHOLOGIA-PAEDAGOGIA SOCIOLOGIA THEOLOGIA CATHOLICA THEOLOGIA CATHOLICA LATIN THEOLOGIA GR.-CATH. VARAD THEOLOGIA ORTHODOXA THEOLOGIA REF. TRANSYLVAN
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Autori: LUCIA IACOBINA TIMIS, MARIA GOREA, CARMEN COSTACHE, IOANA ALINA COLOSI, PAVEL ȘCHIOPU, PAUL-ȘTEFAN PANAITESCU, ADA DELEAN, DINU IULIU DUMITRASCU, RADU SEPTIMIU CÂMPIAN.
DOI: 10.24193/subbchem.2021.4.27
Published Online: 2021-12-30
Published Print: 2021-12-30
pp. 369-382
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The aim of this work was to evaluate the antimicrobial effectiveness of a bioceramic experimental endodontic sealer (EES), alongside with its components. As a novelty, magnesium silicate was incorporated into the experimental material, in order to improve the mechanical performance of the product. The main oxide components, tricalcium silicate (Ca3SiO5) and magnesium silicate (Mg2SiO4) were synthesized in nanoparticles from specific precursors by a sol-gel method. To compare the efficiency of the new developed product, commercially available materials, with similar chemical composition, used in everyday practice, were also tested: BC Sealer, MTA Bioceramic Root Canal Sealer, and MTA Fillapex. The method employed for the present study was the agar well diffusion test (ADT). The selected microbial strains were Enterococcus faecalis and Candida albicans, frequently associated with persistent infection and recurrent infections of the endodontic space, as well as periapical pathologies refractory to endodontic treatment. Measurements of the inhibition areas were performed at 24-hour intervals for 7 consecutive days. Tricalcium silicate and all tested endodontic sealers revealed antimicrobial effectiveness against Candida albicans at 24 hours after placement, with a prolonged activity, for up to 7 days. The study revealed no antibacterial effect against Enterococcus faecalis at 24 hours nor in the following 7 days, for any of the tested samples.
Keywords: antimicrobial activity, bioceramic, endodontic sealer, tricalcium silicate
