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    STUDIA BIOLOGIA - Ediţia nr.2 din 2014  
         
  Articol:   CHRONIC ADMINISTRATION OF RED BULL AFFECTS BLOOD PARAMETERS IN RATS.

Autori:  CAMELIA MUNTEANU, IOAN UŢIU, CORINA-LUMINIŢA ROŞIORU, CAMELIA LANG.
 
       
         
  Rezumat:  VIEW PDF: CHRONIC ADMINISTRATION OF RED BULL AFFECTS BLOOD PARAMETERS IN RATS

Energy drinks are commercial drinks conceived in order to improve physical and intellectual performance. Short term effects of energy drinks are known and do not seem to affect the state of health, but long term effects are less known and raise serious health questions. In this work we investigated if Red Bull affects morphologic and some of the biochemical parameters of the blood. Twenty adult Wistar rats, weighing 186.6±3.15 g were organized into two groups. The Control (C) group received a standard diet and tap water. The animals in the energy drink (ED) group were orally administrated 1.5 ml/100 g b.wt. of Red Bull daily, for 4 weeks. After 4 weeks of treatment, the rats were killed by exsanguination and blood samples were collected for morphologic and biochemical parameter analysis. A significant reduction in red blood cell count was noticed in the ED group, while the hemoglobin concentration and the hematocrit slightly increased in the experimental group, as compared to the control. The concentrations of glucose and total cholesterol increased significantly after Red Bull administration, as did the activities of serum LDH, AST and ALT. These results indicate that a long-term consumption of energy drinks can affect certain morphological and biochemical blood parameters. Furthermore, these drinks may be risk factors for the development of a metabolic disease. 

 Keywords: blood, caffeine, energy drinks, Red Bull
 
         
     
         
         
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