Rezumat articol ediţie STUDIA UNIVERSITATIS BABEŞ-BOLYAI

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Diisocyanates are widely used in the manufacture of flexible and rigid foams, fibers, and coatings such as paints and varnishes, and elastomers. They are known to cause occupational asthma but little is known about the development of the disease in a cohort of workers followed prior and after the exposure occurrence. Our study is a follow up aiming to sample and monitor the air at workplaces for toluene diisocyanate (TDI) in a Polyurethane Foam Factory located in Baia Mare, Romania and assess respiratory health among participants through questionnaire responses and also to measure TDI antibodies in blood serum. In this respect, blood samples were collected from 49 workers included in the study. An interview was conducted with each participant in order to collect health data through a questionnaire. Spirometry was performed to explore the pulmonary function. Further evaluation is necessary including monitoring of the pulmonary function and serum antibodies in order to prevent or/and early identify occupational asthma among those workers with TDI exposure.

Key words: TDI, cohort study, health questionnaire, spirometry